A new publication on the ribotoxic stress response and UV is now online in Molecular Cell

Vind et al. shows that:

•  Skin cells get damaged by UV light, which causes ribosomal stress and initiates a ZAKa-driven inflammatory response and cell death.
• The ribotoxic stress response underlies the acute inflammatory reaction in skin after UV exposure.
• Like UV, anisomycin also provokes ZAKa-dependent swelling, inflammation and epidermal thickening of skin.

 

Read more about the collaborative work here: The ribotoxic stress response drives acute inflammation, cell death, and epidermal thickening in UV-irradiated skin in vivo: Molecular Cell

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